Identification of mouse H-2 antigens by mixed lymphocyte culture in the presence of PHA. 3. Blastformation of mouse lymphocytes according to the difference in non- H-2 antigens.

It has been demonstrated that by the mixed cultures in the presence of PHA the combination of those cells whose H-2 antigens differ from each other shows a higher rate and more significant difference of blastformation than in the combination where non-H-2 antigens differ (Table 1). The blastformation observable in the combinations where non-H-2 histocompatibility antigens or sex.linked antigens are weaker, is not, so marked as the difference seen of the blastformation in the case with H-2 isoantigens. This in vitro lymphocyte stimulation test can be applied to the histocompatibility test in the combinations of strong H-2 antigens. ∗PMID: 4242842 [PubMed indexed for MEDLINE] Copyright c ©OKAYAMA UNIVERSITY MEDICAL SCHOOL Acta Merl. Okayama 23, 203-207 (1969) IDENTIFICATION OF MOUSE H.2 ANTIGENS BY MIXED LYMPHOCYTE CULTURE IN THE PRESENCE OF PHA Ill. BLASTFORMATION OF MOUSE LYMHOCYTES ACCORDING TO THE DIFFERENCE IN NON. H-2 ANTIGENS